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  • The Effects of Limonene and Holy Basil Tea on Staphylococcus epidermidis Biofilm Growth as a Supplement in Conjunction with Tetracycline

    Description:
    In recent years, scientists have come to understand that the effective life span of antimicrobial agents is limited, due to the current crisis pertaining to the rapid emergence of resistant bacteria that is occurring worldwide. As a result, numerous studies have been, and continue to be, conducted in order to find natural alternative sources of antimicrobial agents, with particular interest in sourcing them from plants. The aim of this study is to explore the inhibitory effects of limonene and holy basil tea on Staphylococcus epidermidis biofilms, as well as to observe any synergistic interactions between these agents and the broad-spectrum antibiotic tetracycline that may amplify the inhibition of these biofilms. Limonene and holy basil tea are both plant-based treatments, sourced from the oil of citrus fruits, and from holy basil, respectively. A traditional crystal violet (CV) biofilm assay was used to test the effectiveness of these agents in inhibiting the growth of S. epidermidis biofilms. Trends thus far indicate that these test agents possess antibacterial activity with which to inhibit the formation of S. epidermidis biofilms.
    Subject:
    Biochemistry
    Creator:
    Tamasar, Akshaye
    Contributor:
    Jill Callahan, Thesis Advisor
    Owner:
    lsquillante@saintpeters.edu
    Publisher:
    Saint Peter's University
    Date Uploaded:
    08/16/2023
    Date Modified:
    08/16/2023
    Rights Statement:
    In Copyright
    Resource Type:
    Research Paper

  • The Effects that Escherichia coli Has on the Development of Hemolytic Uremic Syndrome (HUS) and Its Corresponding Treatment

    Description:
    Escherichia coli (E. coli) is a kind of bacterium that is frequently observed in both human and animal digestive tracts. While the majority of E. coli strains are harmless, some are pathogenic and can have substantial negative effects on health. Hemolytic Uremic Syndrome (HUS), a disorder that can result in renal failure, anemia, and low platelet count, is one such consequence. Exposure to specific E. coli strains, especially those that generate Shiga toxin, is frequently linked to the development of HUS. A specific Shiga-toxin generating strain is OH157:H7 and it is known for being linked to a majority of HUS developments. This particular strain will be examined in further depth according to multiple studies done by various researchers. Even though the OH15:H7 strain is quite apparent concerning HUS, other strains will be discussed because many other diagnoses of HUS have been linked to other E. coli strains throughout the world. HUS is an extremely impactful disease that currently has no cure. There are many different ways in which to treat HUS in its developing stages and onset stages, but there have also been studies that discuss the possible negative effects of antibiotic treatment. This paper seeks to inform about the effects E. coli has on developing HUS and its varying treatment options through the most current studies.
    Subject:
    Biology
    Creator:
    Tolentino, Luis
    Contributor:
    Jill Callahan, Thesis Advisor
    Owner:
    lsquillante@saintpeters.edu
    Publisher:
    Saint Peter's University
    Date Uploaded:
    06/13/2023
    Date Modified:
    06/13/2023
    Rights Statement:
    In Copyright
    Resource Type:
    Research Paper