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Mercado, Chiara Ximena
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- Description:
- Candida albicans is one of the most prominent forms of Candidiasis, accounting for more than 75% of all Candidal infections. Aside from its growing prevalence, it is also becoming one of the most resistant strains against antifungal medication. This increase in resistance to allopathic medication has fueled a homeopathic movement in medicine. Homeopathy has recently become a well-known alternative to traditional allopathic medication and has shown success in inhibiting fungal growth in certain strains. Due to the growing amount of resistant strains of fungi due to adaptation to antifungal medication mechanisms, seeking alternative treatments can prevent the rise of a fungal epidemic resistant to known treatments. In this study, 5 separate antifungal agents will be tested on their efficacy of inhibiting fungal growth and their fungicidal properties on cultured C. albicans on Sabouraud dextrose agar plates. The agents being tested are Eucalyptus globulus, Ocimum basilicum, Boiron Benzoicum Acidum 30c, Kali Iodatum 30c, and 100mg Ketoconazole. Growth inhibition rate and fungicidal properties were tested using individual treatment. Results showed that in the growth inhibition trial, Ocimum basilicum had the largest zone of inhibition with Eucalyptus globulus following. The allopathic group showed similar inhibition rates with Benzoicum Acidum and Kali Iodatum showing more inhibition than allopathic Ketoconazole. Fungicidal efficacy was tested in a similar protocol. Data showed that no individual agent had an effective fungicidal effect on Candida albicans, only causing a minimal reduction on the surface in the fungal colony. All data was analyzed using the ANOVA statistical analysis method, and all trials were replicated 10 times to minimize human error and obtain clear results.
- Subject:
- Biology
- Creator:
- Mercado, Chiara Ximena
- Contributor:
- Dr. Brandy Garrett Kluthe, Thesis Advisor
- Owner:
- lsquillante@saintpeters.edu
- Publisher:
- Saint Peter's University
- Date Uploaded:
- 06/09/2020
- Date Modified:
- 06/09/2020
- Date Created:
- April 20, 2020
- Rights Statement:
- In Copyright
- Resource Type:
- Research Paper