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  • A Comparative Study of Homeopathic Alternatives vs Allopathic Treatments on Candida albican Testing Growth Inhibition and Fungicidal Properties

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    Description:
    Candida albicans is one of the most prominent forms of Candidiasis, accounting for more than 75% of all Candidal infections. Aside from its growing prevalence, it is also becoming one of the most resistant strains against antifungal medication. This increase in resistance to allopathic medication has fueled a homeopathic movement in medicine. Homeopathy has recently become a well-known alternative to traditional allopathic medication and has shown success in inhibiting fungal growth in certain strains. Due to the growing amount of resistant strains of fungi due to adaptation to antifungal medication mechanisms, seeking alternative treatments can prevent the rise of a fungal epidemic resistant to known treatments. In this study, 5 separate antifungal agents will be tested on their efficacy of inhibiting fungal growth and their fungicidal properties on cultured C. albicans on Sabouraud dextrose agar plates. The agents being tested are Eucalyptus globulus, Ocimum basilicum, Boiron Benzoicum Acidum 30c, Kali Iodatum 30c, and 100mg Ketoconazole. Growth inhibition rate and fungicidal properties were tested using individual treatment. Results showed that in the growth inhibition trial, Ocimum basilicum had the largest zone of inhibition with Eucalyptus globulus following. The allopathic group showed similar inhibition rates with Benzoicum Acidum and Kali Iodatum showing more inhibition than allopathic Ketoconazole. Fungicidal efficacy was tested in a similar protocol. Data showed that no individual agent had an effective fungicidal effect on Candida albicans, only causing a minimal reduction on the surface in the fungal colony. All data was analyzed using the ANOVA statistical analysis method, and all trials were replicated 10 times to minimize human error and obtain clear results.
    Keyword:
    Kali Iodatum, candida albicans, homeopathy, Ocimum basilicum, candidaisis, Boiron Benzoicum Acidum, Ketoconazole, allopathy, and Eucalyptus globulus
    Subject:
    Biology
    Creator:
    Mercado, Chiara Ximena
    Contributor:
    Dr. Brandy Garrett Kluthe, Thesis Advisor
    Owner:
    lsquillante@saintpeters.edu
    Publisher:
    Saint Peter's University
    Date Uploaded:
    06/09/2020
    Date Modified:
    06/09/2020
    Date Created:
    April 20, 2020
    Rights Statement:
    In Copyright
    Resource Type:
    Research Paper

  • The Potential Use of Selected Organic Natural Products, Individually and in Combination, as Antifungal and Antibacterial Agents Against Candida albicans

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    Description:
    The purpose of this research was to determine the antifungal and antibacterial properties of organic raw honey, organic castor oil, and holy basil (Ocimum tenuiflorum). The fungus, Candida albicans, and microbes found in common places were used to conduct the experiment. These organic solutions possess antibacterial and antifungal properties. There were several groups observed in this experiment: the control, honey vs. fungi, honey vs. bacteria, castor vs. fungi, castor vs. bacteria, honey/castor mix vs. fungi, honey/castor mix vs. bacteria, holy basil vs. fungi, and holy basil vs. bacteria. The petri dishes were first made by making nutrient agar. Afterwards, the C. albicans samples were spread onto the plates and incubated for several days. Once the fungus grew, the organic solutions were placed onto them and left alone for one day in the incubator. The same steps were taken for the bacterial part of the experiment. Results showed that all the plates with honey and castor oil had the best effect against the fungi. Castor oil by itself had zones of inhibition indicating no growth around the areas where the oil was placed. The honey was only effective in high dosages. Lastly, the holy basil was effective in regard to its antibacterial and antifungal activity. This study helped investigate which solution was more suitable to use in modern medicine to fight fungal and bacterial infections, more specifically, Candidiasis.
    Keyword:
    holy basil (ocimum tenuiflorum), candida albicans, natural medicine, candidiasis, organic castor oil, antibacterial, antifungal, and organic raw honey
    Subject:
    Biology
    Creator:
    Patel, Bhavtik
    Contributor:
    Dr. Laura Twersky, Thesis Advisor
    Owner:
    lsquillante@saintpeters.edu
    Publisher:
    Saint Peter's University
    Date Uploaded:
    06/09/2020
    Date Modified:
    06/09/2020
    Date Created:
    April 20, 2020
    Rights Statement:
    In Copyright
    Resource Type:
    Research Paper