Peacock Scholarship

The Effects that Escherichia coli Has on the Development of Hemolytic Uremic Syndrome (HUS) and Its Corresponding Treatment

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Escherichia coli (E. coli) is a kind of bacterium that is frequently observed in both human and animal digestive tracts. While the majority of E. coli strains are harmless, some are pathogenic and can have substantial negative effects on health. Hemolytic Uremic Syndrome (HUS), a disorder that can result in renal failure, anemia, and low platelet count, is one such consequence. Exposure to specific E. coli strains, especially those that generate Shiga toxin, is frequently linked to the development of HUS. A specific Shiga-toxin generating strain is OH157:H7 and it is known for being linked to a majority of HUS developments. This particular strain will be examined in further depth according to multiple studies done by various researchers. Even though the OH15:H7 strain is quite apparent concerning HUS, other strains will be discussed because many other diagnoses of HUS have been linked to other E. coli strains throughout the world. HUS is an extremely impactful disease that currently has no cure. There are many different ways in which to treat HUS in its developing stages and onset stages, but there have also been studies that discuss the possible negative effects of antibiotic treatment. This paper seeks to inform about the effects E. coli has on developing HUS and its varying treatment options through the most current studies.

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  • 06/13/2023
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